Benzene Exposure & Leukemia
Benzene is a common industrial chemical and a known human carcinogen. For families, the harm doesn’t look like a “chemical exposure.” It looks like a diagnosis that hits like a catastrophe: acute myeloid leukemia (AML), bone marrow failure, repeated hospitalizations, intensive chemotherapy, transplant discussions, life-threatening infections, and too often wrongful death.
Benzene can damage the bone marrow and blood-forming system, and long-term exposure has been associated with AML and related disorders. IARC classifies benzene as carcinogenic to humans (Group 1) based on sufficient evidence, including leukemia risk. This page is about the cases where that outcome wasn’t inevitable, where exposure was preventable, controls were available, and the people responsible still allowed benzene risk to reach workers and communities.


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Where benzene exposure happens in real life
Benzene is closely tied to fuel and industrial solvent pathways, meaning exposure can show up in both routine jobs and “nobody thought about it” environments, including:
- Refineries, petrochemical plants, terminals, and tank farms
- Fuel transfer, loading racks, trucking, and bulk storage
- Industrial degreasing/solvent use and certain manufacturing settings
- Work around gas stations or areas near petroleum operations
- Hazardous waste sites and contaminated areas
Some exposures are chronic and subtle: breathing zone exposure over years. Others are acute spikes (spills, confined spaces, poor ventilation) layered on top of chronic risk.
The illnesses that turn benzene cases into catastrophic injury
In Benzene isn’t just “irritating.” The major concern is what it can do to the blood and bone marrow:
- Acute Myeloid Leukemia (AML) – the leukemia most consistently linked with benzene exposure
- Myelodysplastic syndromes (MDS) and bone marrow failure pathways that can progress to AML
- Severe anemia and immune suppression that can lead to repeated, life-threatening complications
Catastrophic harm often comes from the cascade: immunosuppression, sepsis risk, bleeding events, organ complications, and the brutal toll of treatment.


What “preventable exposure” looks like (and what it doesn’t)
Benzene cases often come down to whether the responsible parties treated benzene as a known high-risk hazard or as “part of the job.”
OSHA regulates benzene exposure with a permissible exposure limit of 1 ppm (8-hour TWA) and 5 ppm (15-minute STEL), reflecting how seriously the hazard is treated when it’s measured and controlled.
NIOSH’s pocket guide also summarizes exposure limits and hazard characteristics used in industrial hygiene practice.
In litigation terms, we focus on whether reasonable protections were used: monitoring, ventilation, closed-transfer systems, appropriate PPE/respiratory protection when needed, training, spill response, and accurate hazard communication.
What to do if you or a loved one has leukemia and a benzene exposure history
If you’re in the middle of treatment, your first job is health. Your second is preserving the story while it’s still retrievable.
Save and request:
- Diagnosis records (pathology, cytogenetics, treatment course)
- A simple exposure timeline (jobs, sites, duties, years; fuel/solvent contact; spills/events)
- Training materials, SDS sheets, air monitoring records, fit testing/PPE records (if available)
- Coworker names who can confirm day-to-day exposure conditions


How we build benzene-leukemia toxic tort cases
These cases are built on evidence, medical and industrial, working together:
Medical proof
- Confirming the diagnosis and clinical course
- Reviewing whether the presentation fits known benzene-related hematologic injury patterns
Exposure proof
- Job tasks and intensity (what was handled, how, and how often)
- Whether exposure controls were present or absent, despite known standards
Responsibility proof
- Identifying the entities controlling the site, process, and safety decisions
- Connecting failures in control/warning to the exposure that mattered
When the cost is a life, “we didn’t know” isn’t good enough
Leukemia is a catastrophic diagnosis: physically, financially, and emotionally. If benzene exposure played a role, your case deserves a serious toxic tort investigation that treats the exposure as the central event it was, not an afterthought.
If you’re facing AML or grieving a wrongful death and there’s a history of fuel, solvent, refinery, or industrial exposure, McEldrew Purtell can evaluate whether preventable benzene exposure is part of the story and pursue accountability that matches the scale of the harm.

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